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Real members of MyOsteoTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyOsteoTeam Member asked a question 💭
Ireland, IN
September 8
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That's a really common concern among people taking Prolia (denosumab) for osteoporosis. Gastrointestinal issues are a known side effect of Prolia, which can include things like nausea and diarrhea.

While IBS specifically isn't listed as a direct side effect, digestive discomfort is something many people on Prolia do Show Full Answer

That's a really common concern among people taking Prolia (denosumab) for osteoporosis. Gastrointestinal issues are a known side effect of Prolia, which can include things like nausea and diarrhea.

While IBS specifically isn't listed as a direct side effect, digestive discomfort is something many people on Prolia do experience. Here are a few things worth knowing:

- Gastrointestinal issues like nausea and diarrhea are among the more common side effects
- Fatigue, headache, and bone or muscle pain are also commonly reported
- Rarely, Prolia can cause very low calcium levels, so it's worth keeping an eye on that too

It's really important to bring this up with a doctor, especially if the symptoms are affecting daily life. They can help figure out whether Prolia is the likely cause and discuss options. Other MyOsteoTeam members have shared that managing side effects from osteoporosis treatments can be challenging, and it's one of the most talked-about topics. Knowing others are navigating similar experiences can make it feel a little less overwhelming!

September 8

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