What are the likely side effects of Prolia if you're medication-intolerant?
It's understandable to be concerned about side effects, especially when you've had a difficult experience with alendronic acid. Prolia (Denosumab) is given as an injection every six months and works differently than bisphosphonates.
Common side Show Full Answer
What are the likely side effects of Prolia if you're medication-intolerant?
It's understandable to be concerned about side effects, especially when you've had a difficult experience with alendronic acid. Prolia (Denosumab) is given as an injection every six months and works differently than bisphosphonates.
Common side effects of Prolia include:
- Bone or muscle pain
- Gastrointestinal issues like nausea or diarrhea
- Fatigue
- Headache
- Frequent nighttime urination (reported by some MyOsteoTeam members)
Rare but serious side effects can include:
- Very low calcium levels
- Osteonecrosis (bone death) of the jaw, especially after dental surgery
- Increased risk of spinal fractures if stopped suddenly
Interestingly, studies show that after 12 months of taking Prolia, bone pain actually improves in most people, which might be helpful given your arthritis concerns.
Since you're very intolerant of medications, it's crucial to discuss this thoroughly with your doctor. They can help weigh the benefits against potential risks and monitor you closely. Some members find certain osteoporosis medications more tolerable than others, so what didn't work with one drug doesn't necessarily predict how you'll respond to another.
Make sure to stay on schedule with Prolia if you start it, as stopping suddenly can increase fracture risk.
March 26
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