I tried Tymlos for about 5 weeks last summer. Probably 4 out of the 5 weeks, the next day I could hardly get off of the couch, even to eat. The shot knocked me out. My endo said he had never heard of that side affect, but that is a fairly common affect listed. Then he kept after me to get the Prolia shots, but after a lot of research, I said No and No.
Have been taking AlgaeCal since last summer.
Everyone is different tho. Read and research.